The different phases of the interstellar medium provide information on the evolutionary state of galaxies and those hosting AGN. We are using ALMA to study the cold molecular gas and dust content of galaxies in the distant universe (z > 1) where star formation and black hole growth peaked. Multi-object spectroscopy (FMOS, PFS) in the infrared provides key diagnostic emission lines to measure the chemical composition, ionization state, and density of the warm ISM. With many targets falling within the COSMOS-Web survey, JWST imaging provides the needed detection of the underlying stars and those obscured within the central bulges. 
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